Best Enzymatic Cleaner for Cat Urine – Top 5 Products

Enzymatic cleaners are a great way to eliminate tough cat urine stains and odors.

They are highly effective, safe for use around cats, and contain no harsh chemicals.

This guide will discuss the best enzymatic cleaner for cat urine, how to use it correctly, and its importance for cat urine removal.

Also, it will shed light on homemade cleaners.

Table of Contents

What Is the Best Way to Clean Up Cat Urine?

Clean It Asap

If you don’t clean it asap, the urea in it decomposes, emitting a foul odor. Of course, you might never have to deal with urine odor again if you can spot it before it decomposes (and clean it up). 

Use A Black Light

Cat urine can dry up before you clean it up, but don’t worry. Just use a black light to spot the thing and clean it up. However, you might need to clean the area several times to eliminate that stain. Of course, black-light torches are affordable. 

Use Enough Cleaning Solution

First, blot the stained area to remove as much urine as possible from the spot before applying an enzymatic cleaner. 

Next, apply your favorite enzymatic cleaner – please follow the manufacturer’s instructions in the letter.

For effective permanence, use a lot of the cleaning solution to saturate the stained spot, especially if the stained area is on a porous material like a carpet or rug.

I recommend you apply your enzymatic cleaner twice the size of the stained area.

The goal is to get the cleaning liquid to flow through the porous material to flush out the urine thoroughly.

Allow Drying Thoroughly

Let the area dry up entirely before attempting to benchmark results. Wet surfaces tend to stink more than dry areas.

That’s why old, dry urine with a mild smell can have a strong odor when applying enzymatic cleaner.

Best Enzymatic Cleaner for Cat Urine

1. THORNELL Cat-Odor-Off Cleaner

THORNELL Cat-Odor-Off Cleaner

Advantages & Disadvantages

  • Firstly, it eliminates urine odor permanently.
  • Next, the treated areas will be safe for your cat.
  • Besides, this cleaner is easy to use and is compatible with many surfaces – litter, floors, walls, rugs, etc.
  • Also, it’s high quality, and veterinarians recommend it.
  • However, it has a strong scent; some cats may not like it.

Customer Reviews

“It does a good job of eliminating the cat pee smell and replacing it with a strong rosemary-pine scent.”

2. Rocco & Roxie Eliminator for Strong Odor

Rocco & Roxie Eliminator for Strong Odor

Advantages & Disadvantages

  • Firstly, it has no hazardous ingredients and is safe for pets and children.
  • Additionally, it’s suitable on all surfaces, including furniture, clothing, and floors.
  • Again, it’s a #1 best seller in odor removers.
  • Notwithstanding, it has a higher price tag.

Customer Reviews

“Follow the directions, and you will have a clean, nice-smelling result.”



Advantages & Disadvantages

  • Firstly, it’s a bio-enzymatic spray and eliminates stains and odors.
  • Secondly, it has no chemical propellants and is cat-friendly.
  • Plus, if you’re unsatisfied with your order, you can return it.
  • Furthermore, it has an excellent overall rating, and thousands of previous buyers recommend it.
  • Conversely, you’ll need much of this product to clean urine stains.

Customer Reviews

“This is an effective product that does more than just cover the smell.”

4. Nature’s Miracle Stain and Odor Remover

Nature’s Miracle Stain and Odor Remover

Advantages & Disadvantages

  • Firstly, it removes tough urine stains and odors.
  • Then, the brand (Nature’s Miracle) that makes it is reputable.
  • In addition, it comes with usage instructions, and first-time users can use it stress-free.
  • Moreover, it is safe on multiple surfaces: carpets, hardwood, tiles, etc.
  • Nevertheless, this cleaner has a strong scent and can be overwhelming for cats.

Customer Reviews

“Stains come out effortlessly (no scrubbing).”

5. TriNova Natural Stain and Odor Eliminator

TriNova Natural Stain and Odor Eliminator

Advantages & Disadvantages

  • Firstly, it is a natural cleaner and contains 100% organic ingredients.
  • Likewise, its blend of enzymes effectively removes urine odors and stains.
  • Plus, it comes with a money-back guarantee.
  • Besides, it has a formula that will keep cleaned areas safe for your cat.
  • Regardless, the scent is powerful, and your kitty may not like it.

Customer Reviews

“Unbelievable product. Removed years of pee stains (stains that would reappear after shampooing).”

Homemade Cleaning Solution for Pet Urine

Homemade Enzyme Cleaner

Unfortunately, homemade enzyme cleaners aren’t as effective as the ones in stores.

For example, suppose you attempt to make an enzymatic home cleaner.

In that case, unless you know the correct enzyme to use as an ingredient, the chemical process of breaking down the urine to clean it will be unlikely happen.

Homemade Vinegar Cleaner

Homemade vinegar can remove cat urine odor – take 1 part of vinegar and two parts of water, then mix them in a spray bottle.

Next, spray the thing on the stained surface and clean it with a paper towel.

There’s a catch, though – this cleaner isn’t effective on porous surfaces (carpets, rugs, etc.) but on non-porous surfaces (tiles, hardwood, etc.).


With a suitable enzymatic cleaner and proper usage, you can eliminate cat urine odors quickly and effectively. For more information, contact us today.